node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHR32539.1 | EHR32540.1 | HMPREF9709_01470 | HMPREF9709_01471 | Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | AgaS family putative sugar isomerase. | 0.850 |
EHR32539.1 | lacD | HMPREF9709_01470 | HMPREF9709_01472 | Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | Tagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family. | 0.974 |
EHR32539.1 | pfkA | HMPREF9709_01470 | HMPREF9709_00396 | Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.943 |
EHR32539.1 | pfp | HMPREF9709_01470 | HMPREF9709_01274 | Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | Hypothetical protein; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.942 |
EHR32540.1 | EHR32539.1 | HMPREF9709_01471 | HMPREF9709_01470 | AgaS family putative sugar isomerase. | Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 0.850 |
EHR32540.1 | EHR32551.1 | HMPREF9709_01471 | HMPREF9709_01482 | AgaS family putative sugar isomerase. | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 0.677 |
EHR32540.1 | EHR36275.1 | HMPREF9709_01471 | HMPREF9709_00030 | AgaS family putative sugar isomerase. | 1-phosphofructokinase family hexose kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 0.551 |
EHR32540.1 | lacD | HMPREF9709_01471 | HMPREF9709_01472 | AgaS family putative sugar isomerase. | Tagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family. | 0.938 |
EHR32540.1 | pfkA | HMPREF9709_01471 | HMPREF9709_00396 | AgaS family putative sugar isomerase. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.536 |
EHR32540.1 | pfp | HMPREF9709_01471 | HMPREF9709_01274 | AgaS family putative sugar isomerase. | Hypothetical protein; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.536 |
EHR32551.1 | EHR32540.1 | HMPREF9709_01482 | HMPREF9709_01471 | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | AgaS family putative sugar isomerase. | 0.677 |
EHR32551.1 | EHR36275.1 | HMPREF9709_01482 | HMPREF9709_00030 | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 1-phosphofructokinase family hexose kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 0.865 |
EHR32551.1 | lacD | HMPREF9709_01482 | HMPREF9709_01472 | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | Tagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family. | 0.853 |
EHR32551.1 | pfkA | HMPREF9709_01482 | HMPREF9709_00396 | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.943 |
EHR32551.1 | pfp | HMPREF9709_01482 | HMPREF9709_01274 | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | Hypothetical protein; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.942 |
EHR33293.1 | lacD | HMPREF9709_01337 | HMPREF9709_01472 | Transcriptional activator, Rgg/GadR/MutR family domain-containing protein. | Tagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family. | 0.764 |
EHR34014.1 | lacD | HMPREF9709_00950 | HMPREF9709_01472 | Hypothetical protein; Belongs to the aldehyde dehydrogenase family. | Tagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family. | 0.700 |
EHR34443.1 | lacD | HMPREF9709_00750 | HMPREF9709_01472 | Hypothetical protein. | Tagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family. | 0.674 |
EHR36060.1 | lacD | HMPREF9709_00156 | HMPREF9709_01472 | Hypothetical protein. | Tagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family. | 0.674 |
EHR36275.1 | EHR32540.1 | HMPREF9709_00030 | HMPREF9709_01471 | 1-phosphofructokinase family hexose kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | AgaS family putative sugar isomerase. | 0.551 |