| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKU77949.1 | EKU78998.1 | HMPREF9282_01507 | HMPREF9282_00795 | Hypothetical protein. | Hypothetical protein. | 0.748 |
| EKU77949.1 | bioW | HMPREF9282_01507 | HMPREF9282_01307 | Hypothetical protein. | 6-carboxyhexanoate-CoA ligase; Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP. | 0.440 |
| EKU78200.1 | EKU78202.1 | HMPREF9282_01306 | HMPREF9282_01308 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Hypothetical protein. | 0.483 |
| EKU78200.1 | EKU78786.1 | HMPREF9282_01306 | HMPREF9282_00583 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Iron-only hydrogenase maturation rSAM protein HydE. | 0.717 |
| EKU78200.1 | argD | HMPREF9282_01306 | HMPREF9282_01065 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Acetylornithine and succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.801 |
| EKU78200.1 | bioA | HMPREF9282_01306 | HMPREF9282_00595 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.947 |
| EKU78200.1 | bioB | HMPREF9282_01306 | HMPREF9282_01313 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.826 |
| EKU78200.1 | bioD | HMPREF9282_01306 | HMPREF9282_00594 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.951 |
| EKU78200.1 | bioW | HMPREF9282_01306 | HMPREF9282_01307 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 6-carboxyhexanoate-CoA ligase; Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP. | 0.994 |
| EKU78202.1 | EKU78200.1 | HMPREF9282_01308 | HMPREF9282_01306 | Hypothetical protein. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.483 |
| EKU78202.1 | bioW | HMPREF9282_01308 | HMPREF9282_01307 | Hypothetical protein. | 6-carboxyhexanoate-CoA ligase; Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP. | 0.788 |
| EKU78786.1 | EKU78200.1 | HMPREF9282_00583 | HMPREF9282_01306 | Iron-only hydrogenase maturation rSAM protein HydE. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.717 |
| EKU78786.1 | argD | HMPREF9282_00583 | HMPREF9282_01065 | Iron-only hydrogenase maturation rSAM protein HydE. | Acetylornithine and succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.589 |
| EKU78786.1 | bioA | HMPREF9282_00583 | HMPREF9282_00595 | Iron-only hydrogenase maturation rSAM protein HydE. | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.589 |
| EKU78786.1 | bioD | HMPREF9282_00583 | HMPREF9282_00594 | Iron-only hydrogenase maturation rSAM protein HydE. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.963 |
| EKU78786.1 | bioW | HMPREF9282_00583 | HMPREF9282_01307 | Iron-only hydrogenase maturation rSAM protein HydE. | 6-carboxyhexanoate-CoA ligase; Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP. | 0.654 |
| EKU78998.1 | EKU77949.1 | HMPREF9282_00795 | HMPREF9282_01507 | Hypothetical protein. | Hypothetical protein. | 0.748 |
| EKU78998.1 | bioW | HMPREF9282_00795 | HMPREF9282_01307 | Hypothetical protein. | 6-carboxyhexanoate-CoA ligase; Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP. | 0.472 |
| argD | EKU78200.1 | HMPREF9282_01065 | HMPREF9282_01306 | Acetylornithine and succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.801 |
| argD | EKU78786.1 | HMPREF9282_01065 | HMPREF9282_00583 | Acetylornithine and succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Iron-only hydrogenase maturation rSAM protein HydE. | 0.589 |