| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKU77928.1 | EKU77930.1 | HMPREF9282_01486 | HMPREF9282_01488 | Hypothetical protein. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.762 |
| EKU77928.1 | EKU77931.1 | HMPREF9282_01486 | HMPREF9282_01489 | Hypothetical protein. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.762 |
| EKU77928.1 | EKU77932.1 | HMPREF9282_01486 | HMPREF9282_01490 | Hypothetical protein. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.737 |
| EKU77928.1 | folE | HMPREF9282_01486 | HMPREF9282_01487 | Hypothetical protein. | GTP cyclohydrolase I. | 0.762 |
| EKU77930.1 | EKU77928.1 | HMPREF9282_01488 | HMPREF9282_01486 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Hypothetical protein. | 0.762 |
| EKU77930.1 | EKU77931.1 | HMPREF9282_01488 | HMPREF9282_01489 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
| EKU77930.1 | EKU77932.1 | HMPREF9282_01488 | HMPREF9282_01490 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.999 |
| EKU77930.1 | EKU78567.1 | HMPREF9282_01488 | HMPREF9282_00364 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Methionine synthase. | 0.653 |
| EKU77930.1 | EKU78678.1 | HMPREF9282_01488 | HMPREF9282_00475 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Hypothetical protein. | 0.885 |
| EKU77930.1 | EKU78679.1 | HMPREF9282_01488 | HMPREF9282_00476 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Aminodeoxychorismate synthase, component I. | 0.790 |
| EKU77930.1 | EKU78680.1 | HMPREF9282_01488 | HMPREF9282_00477 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | GMP synthase (glutamine-hydrolyzing) domain-containing protein. | 0.694 |
| EKU77930.1 | EKU79452.1 | HMPREF9282_01488 | HMPREF9282_00260 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | FolC protein; Belongs to the folylpolyglutamate synthase family. | 0.998 |
| EKU77930.1 | folE | HMPREF9282_01488 | HMPREF9282_01487 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | GTP cyclohydrolase I. | 0.997 |
| EKU77930.1 | guaB | HMPREF9282_01488 | HMPREF9282_01659 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.665 |
| EKU77931.1 | EKU77928.1 | HMPREF9282_01489 | HMPREF9282_01486 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Hypothetical protein. | 0.762 |
| EKU77931.1 | EKU77930.1 | HMPREF9282_01489 | HMPREF9282_01488 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
| EKU77931.1 | EKU77932.1 | HMPREF9282_01489 | HMPREF9282_01490 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.999 |
| EKU77931.1 | EKU78678.1 | HMPREF9282_01489 | HMPREF9282_00475 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Hypothetical protein. | 0.523 |
| EKU77931.1 | EKU79452.1 | HMPREF9282_01489 | HMPREF9282_00260 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | FolC protein; Belongs to the folylpolyglutamate synthase family. | 0.761 |
| EKU77931.1 | folE | HMPREF9282_01489 | HMPREF9282_01487 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I. | 0.997 |