| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKU77707.1 | coaD | HMPREF9282_01925 | HMPREF9282_01932 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.925 |
| EKU77707.1 | coaE | HMPREF9282_01925 | HMPREF9282_02001 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.699 |
| EKU77781.1 | EKU77782.1 | HMPREF9282_01999 | HMPREF9282_02000 | Hypothetical protein. | Hypothetical protein. | 0.592 |
| EKU77781.1 | coaE | HMPREF9282_01999 | HMPREF9282_02001 | Hypothetical protein. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.590 |
| EKU77782.1 | EKU77781.1 | HMPREF9282_02000 | HMPREF9282_01999 | Hypothetical protein. | Hypothetical protein. | 0.592 |
| EKU77782.1 | EKU77784.1 | HMPREF9282_02000 | HMPREF9282_02002 | Hypothetical protein. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.581 |
| EKU77782.1 | coaE | HMPREF9282_02000 | HMPREF9282_02001 | Hypothetical protein. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.839 |
| EKU77782.1 | polA | HMPREF9282_02000 | HMPREF9282_02003 | Hypothetical protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.499 |
| EKU77784.1 | EKU77782.1 | HMPREF9282_02002 | HMPREF9282_02000 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | Hypothetical protein. | 0.581 |
| EKU77784.1 | coaE | HMPREF9282_02002 | HMPREF9282_02001 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.983 |
| EKU77784.1 | polA | HMPREF9282_02002 | HMPREF9282_02003 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.985 |
| EKU79217.1 | coaE | HMPREF9282_00025 | HMPREF9282_02001 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.628 |
| EKU79265.1 | acpP | HMPREF9282_00073 | HMPREF9282_00075 | Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.988 |
| EKU79265.1 | coaE | HMPREF9282_00073 | HMPREF9282_02001 | Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.593 |
| acpP | EKU79265.1 | HMPREF9282_00075 | HMPREF9282_00073 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.988 |
| acpP | acpS | HMPREF9282_00075 | HMPREF9282_01911 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Phosphopantetheine-protein transferase domain; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | 0.916 |
| acpP | coaE | HMPREF9282_00075 | HMPREF9282_02001 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.614 |
| acpP | polA | HMPREF9282_00075 | HMPREF9282_02003 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.677 |
| acpS | acpP | HMPREF9282_01911 | HMPREF9282_00075 | Phosphopantetheine-protein transferase domain; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.916 |
| acpS | coaE | HMPREF9282_01911 | HMPREF9282_02001 | Phosphopantetheine-protein transferase domain; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.792 |