STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASCL3Achaete-scute family bHLH transcription factor 3. (172 aa)    
Predicted Functional Partners:
SHOX2
Short stature homeobox 2.
    
 0.625
TRPM5
Transient receptor potential cation channel subfamily M member 5; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.602
HPGDS
Hematopoietic prostaglandin D synthase.
      
 0.558
SHOX
Short stature homeobox.
    
 0.556
EIF2B3
Uncharacterized protein.
      
 0.546
GHITM
Growth hormone inducible transmembrane protein; Belongs to the BI1 family.
      
 0.546
SH3BGR
Uncharacterized protein.
      
 0.546
BANP
BTG3 associated nuclear protein.
      
 0.546
CFTR
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
      
 0.489
LDB2
LIM domain binding 2.
    
 0.437
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.