Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF223Ring finger protein 223. (227 aa)    
Predicted Functional Partners:
RNF130
Ring finger protein 130.
     
 0.621
RNF144A
RBR-type E3 ubiquitin transferase.
    
 0.605
TMEM129
Transmembrane protein 129.
      
 0.589
MEAF6
MYST/Esa1 associated factor 6.
     
 0.576
RNF144B
RBR-type E3 ubiquitin transferase.
    
 0.559
PERM1
Uncharacterized protein.
    
 0.551
NOC2L
NOC2 like nucleolar associated transcriptional repressor.
      
 0.545
KLHL17
Kelch like family member 17.
    
 
 0.492
SAMD11
Sterile alpha motif domain containing 11.
    
 
 0.467
RNF103
Ring finger protein 103.
     
 0.409
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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