Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (363 aa)    
Predicted Functional Partners:
GNAQ
G protein subunit alpha q.
    
 0.930
P2RX1
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
      
 0.652
P2RX7
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.
      
 0.581
ENSAPLP00000022103
Brix domain-containing protein.
 
  
  0.571
ARL16
Uncharacterized protein.
    
 0.555
P2RX5
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
     
 0.547
ENTPD3
Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family.
      
 0.484
P2RX3
Purinergic receptor P2X 3.
      
 0.484
P2RX2
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.
      
 0.446
GNG5
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.438
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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