Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
RSPO3R-spondin 3. (319 aa)    
Predicted Functional Partners:
LGR4
Leucine rich repeat containing G protein-coupled receptor 4.
   
 0.995
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
   
 0.992
RNF43
RING-type domain-containing protein.
    
 0.981
ZNRF3
Zinc and ring finger 3.
    
 0.962
LGR6
Leucine rich repeat containing G protein-coupled receptor 6.
    
 0.955
FOXL1
Forkhead box L1.
     
 0.740
WNT9B
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
      
 0.669
RPS27A
Ubiquitin-like domain-containing protein.
     
  0.616
RSPO1
R-spondin 1.
     
  0.560
DKK3
Dickkopf WNT signaling pathway inhibitor 3.
   
 
 0.550
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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