STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRY4Sprouty RTK signaling antagonist 4. (299 aa)    
Predicted Functional Partners:
CBLB
Cbl proto-oncogene B.
    
 0.741
CBL
Cbl proto-oncogene.
    
 0.741
DUSP6
Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
   
  
 0.702
SPRY1
Sprouty RTK signaling antagonist 1.
   
0.613
ETV4
ETS variant 4.
   
  
 0.610
FGF8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
   
  
 0.604
ETV5
ETS domain-containing protein.
   
  
 0.565
IL17RD
Interleukin 17 receptor D.
      
 0.555
GRB2
Growth factor receptor bound protein 2.
    
 0.551
FGF10
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
   
  
 0.541
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.