STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATF4Activating transcription factor 4. (354 aa)    
Predicted Functional Partners:
U3I0R1_ANAPP
Uncharacterized protein.
   
 0.994
EIF2S1
Eukaryotic translation initiation factor 2 subunit alpha.
    
 0.979
ATF3
Activating transcription factor 3.
    
 0.967
CEBPG
CCAAT enhancer binding protein gamma.
   
 0.952
CREM
cAMP responsive element modulator.
    
 0.949
RPS6KA6
Ribosomal protein S6 kinase.
    
 0.946
ATF2
Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.
    
 0.945
CREB5
Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription.
    
 0.941
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
 
 0.941
RPS6KA3
Non-specific serine/threonine protein kinase.
    
  0.918
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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