STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AP4S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (105 aa)    
Predicted Functional Partners:
AP4E1
Adaptor related protein complex 4 subunit epsilon 1.
    
 0.975
AP4B1
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
    
 0.964
GAK
Cyclin G associated kinase.
   
 
 0.914
AP1G1
AP-1 complex subunit gamma.
    
 0.907
AP1M1
AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
    
 0.892
ENSAPLP00000029632
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
    
 0.892
AP2B1
AP complex subunit beta.
    
 0.835
AP3B1
AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.
   
 
 0.815
AP3D1
Adaptor related protein complex 3 subunit delta 1.
    
 0.789
AP5M1
Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family.
    
 0.774
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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