STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (180 aa)    
Predicted Functional Partners:
KCNS3
Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family.
    
 0.638
CACNG2
Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
      
 0.611
OLFML1
Olfactomedin like 1.
      
 0.586
U3J0T1_ANAPP
Uncharacterized protein.
    
 0.586
KCNQ1
Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.
    
 0.586
ANKRA2
Ankyrin repeat family A member 2.
     
 0.576
TULP4
TUB like protein 4.
      
 0.539
KCNH6
Potassium voltage-gated channel subfamily H member 6.
     
 0.510
KCNQ3
Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family.
    
 0.508
KCNE2
Potassium voltage-gated channel subfamily E regulatory subunit 2.
      
 0.497
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.