STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPPL3Signal peptide peptidase like 3. (380 aa)    
Predicted Functional Partners:
APIP
Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.
      
 0.729
TAOK3
TAO kinase 3.
      
 0.650
SH2B3
SH2B adaptor protein 3.
      
 0.618
GOSR1
Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
      
 0.611
PHRF1
PHD and ring finger domains 1.
      
 0.608
SNF8
SNF8 subunit of ESCRT-II.
   
  
 0.538
NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase.
      
 0.487
B3GNT5
Hexosyltransferase.
      
 0.479
LARGE1
LARGE xylosyl- and glucuronyltransferase 1.
      
 0.476
DDX6
DEAD-box helicase 6; Belongs to the DEAD box helicase family.
      
 0.464
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.