DPYS protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DPYS

Dihydropyrimidinase. (530 aa)

Predicted Functional Partners:

DPYD

0.968

UMPS

0.694

DHODH

0.691

LANCL1

0.622

U3ISR6_ANAPP

0.619

GART

0.619

GOLT1B

0.611

GOLT1A

0.611

CYB5R4

0.571

UPB1

0.563

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYB5R4	DHODH	ENSAPLP00000011617	ENSAPLP00000015086	Cytochrome b5 reductase 4.	DHO_dh domain-containing protein.	0.915
CYB5R4	DPYD	ENSAPLP00000011617	ENSAPLP00000011867	Cytochrome b5 reductase 4.	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.	0.915
CYB5R4	DPYS	ENSAPLP00000011617	ENSAPLP00000001326	Cytochrome b5 reductase 4.	Dihydropyrimidinase.	0.571
CYB5R4	GOLT1A	ENSAPLP00000011617	ENSAPLP00000020247	Cytochrome b5 reductase 4.	Golgi transport 1A.	0.572
CYB5R4	GOLT1B	ENSAPLP00000011617	ENSAPLP00000002864	Cytochrome b5 reductase 4.	Golgi transport 1B.	0.572
CYB5R4	UMPS	ENSAPLP00000011617	ENSAPLP00000022193	Cytochrome b5 reductase 4.	Uridine monophosphate synthetase.	0.921
DHODH	CYB5R4	ENSAPLP00000015086	ENSAPLP00000011617	DHO_dh domain-containing protein.	Cytochrome b5 reductase 4.	0.915
DHODH	DPYD	ENSAPLP00000015086	ENSAPLP00000011867	DHO_dh domain-containing protein.	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.	0.489
DHODH	DPYS	ENSAPLP00000015086	ENSAPLP00000001326	DHO_dh domain-containing protein.	Dihydropyrimidinase.	0.691
DHODH	GART	ENSAPLP00000015086	ENSAPLP00000024225	DHO_dh domain-containing protein.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.757
DHODH	GOLT1A	ENSAPLP00000015086	ENSAPLP00000020247	DHO_dh domain-containing protein.	Golgi transport 1A.	0.878
DHODH	GOLT1B	ENSAPLP00000015086	ENSAPLP00000002864	DHO_dh domain-containing protein.	Golgi transport 1B.	0.878
DHODH	U3ISR6_ANAPP	ENSAPLP00000015086	ENSAPLP00000010289	DHO_dh domain-containing protein.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.757
DHODH	UMPS	ENSAPLP00000015086	ENSAPLP00000022193	DHO_dh domain-containing protein.	Uridine monophosphate synthetase.	0.998
DHODH	UPB1	ENSAPLP00000015086	ENSAPLP00000008468	DHO_dh domain-containing protein.	Beta-ureidopropionase 1.	0.549
DPYD	CYB5R4	ENSAPLP00000011867	ENSAPLP00000011617	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.	Cytochrome b5 reductase 4.	0.915
DPYD	DHODH	ENSAPLP00000011867	ENSAPLP00000015086	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.	DHO_dh domain-containing protein.	0.489
DPYD	DPYS	ENSAPLP00000011867	ENSAPLP00000001326	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.	Dihydropyrimidinase.	0.968
DPYD	GART	ENSAPLP00000011867	ENSAPLP00000024225	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.757
DPYD	GOLT1A	ENSAPLP00000011867	ENSAPLP00000020247	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.	Golgi transport 1A.	0.878