STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TIRAPTIR domain containing adaptor protein. (219 aa)    
Predicted Functional Partners:
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
 0.998
TLR4
Toll like receptor 4.
   
 0.996
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.982
IRAK4
Interleukin 1 receptor associated kinase 4.
   
 0.974
TLR2
Toll like receptor 2; Belongs to the Toll-like receptor family.
   
0.963
TLR6
Toll like receptor 6; Belongs to the Toll-like receptor family.
   
 0.958
LY96
Lymphocyte antigen 96.
   
 
 0.953
TOLLIP
Toll interacting protein.
     
 0.885
TBK1
TANK binding kinase 1.
   
 
 0.796
TLR3
Toll like receptor 3; Belongs to the Toll-like receptor family.
   
 0.779
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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