CXCR6 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CXCR6

C-X-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (347 aa)

Predicted Functional Partners:

FYCO1

0.795

KLRG1

0.669

CCL5

0.635

LZTFL1

0.628

SLC6A20

0.609

CXCL12

0.590

CD4

0.582

U3IRV1_ANAPP

0.544

CX3CL1

0.535

IFNG

0.525

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCL5	CD4	ENSAPLP00000017309	ENSAPLP00000018005	C-C motif chemokine.	Ig-like domain-containing protein.	0.743
CCL5	CX3CL1	ENSAPLP00000017309	ENSAPLP00000012081	C-C motif chemokine.	SCY domain-containing protein.	0.769
CCL5	CXCL12	ENSAPLP00000017309	ENSAPLP00000015191	C-C motif chemokine.	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family.	0.985
CCL5	CXCR6	ENSAPLP00000017309	ENSAPLP00000001388	C-C motif chemokine.	C-X-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family.	0.635
CCL5	IFNG	ENSAPLP00000017309	ENSAPLP00000012661	C-C motif chemokine.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.836
CD4	CCL5	ENSAPLP00000018005	ENSAPLP00000017309	Ig-like domain-containing protein.	C-C motif chemokine.	0.743
CD4	CXCL12	ENSAPLP00000018005	ENSAPLP00000015191	Ig-like domain-containing protein.	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family.	0.671
CD4	CXCR6	ENSAPLP00000018005	ENSAPLP00000001388	Ig-like domain-containing protein.	C-X-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family.	0.582
CD4	IFNG	ENSAPLP00000018005	ENSAPLP00000012661	Ig-like domain-containing protein.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.961
CD4	KLRG1	ENSAPLP00000018005	ENSAPLP00000016716	Ig-like domain-containing protein.	Killer cell lectin like receptor G1.	0.621
CX3CL1	CCL5	ENSAPLP00000012081	ENSAPLP00000017309	SCY domain-containing protein.	C-C motif chemokine.	0.769
CX3CL1	CXCL12	ENSAPLP00000012081	ENSAPLP00000015191	SCY domain-containing protein.	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family.	0.900
CX3CL1	CXCR6	ENSAPLP00000012081	ENSAPLP00000001388	SCY domain-containing protein.	C-X-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family.	0.535
CX3CL1	IFNG	ENSAPLP00000012081	ENSAPLP00000012661	SCY domain-containing protein.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.655
CXCL12	CCL5	ENSAPLP00000015191	ENSAPLP00000017309	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family.	C-C motif chemokine.	0.985
CXCL12	CD4	ENSAPLP00000015191	ENSAPLP00000018005	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family.	Ig-like domain-containing protein.	0.671
CXCL12	CX3CL1	ENSAPLP00000015191	ENSAPLP00000012081	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family.	SCY domain-containing protein.	0.900
CXCL12	CXCR6	ENSAPLP00000015191	ENSAPLP00000001388	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family.	C-X-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family.	0.590
CXCL12	IFNG	ENSAPLP00000015191	ENSAPLP00000012661	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.562
CXCR6	CCL5	ENSAPLP00000001388	ENSAPLP00000017309	C-X-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine.	0.635