Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DRAM2DNA damage regulated autophagy modulator 2. (266 aa)    
Predicted Functional Partners:
SPG7
SPG7 matrix AAA peptidase subunit, paraplegin.
      
 0.729
ISCA1
Iron-sulfur cluster assembly 1.
      
 0.715
GPR37
G protein-coupled receptor 37.
      
 0.644
THYN1
Thymocyte nuclear protein 1.
      
 0.597
TTC12
TPR_REGION domain-containing protein.
      
 0.564
C8orf37
Chromosome 8 open reading frame 37.
      
 0.547
PTER
Phosphotriesterase related; Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
      
 0.545
DHX40
DEAH-box helicase 40.
      
 0.545
MEST
Mesoderm specific transcript.
      
 0.531
TNNT3
Troponin T3, fast skeletal type.
      
 0.502
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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