node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BCKDHA | BCKDHB | ENSAPLP00000028925 | ENSAPLP00000019242 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Branched chain keto acid dehydrogenase E1 subunit beta. | 0.999 |
BCKDHA | DLAT | ENSAPLP00000028925 | ENSAPLP00000005029 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.961 |
BCKDHA | ENSAPLP00000024157 | ENSAPLP00000028925 | ENSAPLP00000024157 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.996 |
BCKDHA | GCSH | ENSAPLP00000028925 | ENSAPLP00000029441 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.793 |
BCKDHA | LIAS | ENSAPLP00000028925 | ENSAPLP00000011673 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.551 |
BCKDHA | LIPT1 | ENSAPLP00000028925 | ENSAPLP00000001416 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Lipoyltransferase 1. | 0.861 |
BCKDHA | PDHX | ENSAPLP00000028925 | ENSAPLP00000011507 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.964 |
BCKDHB | BCKDHA | ENSAPLP00000019242 | ENSAPLP00000028925 | Branched chain keto acid dehydrogenase E1 subunit beta. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.999 |
BCKDHB | DLAT | ENSAPLP00000019242 | ENSAPLP00000005029 | Branched chain keto acid dehydrogenase E1 subunit beta. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.946 |
BCKDHB | ENSAPLP00000024157 | ENSAPLP00000019242 | ENSAPLP00000024157 | Branched chain keto acid dehydrogenase E1 subunit beta. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.658 |
BCKDHB | GCSH | ENSAPLP00000019242 | ENSAPLP00000029441 | Branched chain keto acid dehydrogenase E1 subunit beta. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.795 |
BCKDHB | LIPT1 | ENSAPLP00000019242 | ENSAPLP00000001416 | Branched chain keto acid dehydrogenase E1 subunit beta. | Lipoyltransferase 1. | 0.875 |
BCKDHB | OXSM | ENSAPLP00000019242 | ENSAPLP00000007697 | Branched chain keto acid dehydrogenase E1 subunit beta. | 3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.453 |
BCKDHB | PDHX | ENSAPLP00000019242 | ENSAPLP00000011507 | Branched chain keto acid dehydrogenase E1 subunit beta. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.960 |
DLAT | BCKDHA | ENSAPLP00000005029 | ENSAPLP00000028925 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.961 |
DLAT | BCKDHB | ENSAPLP00000005029 | ENSAPLP00000019242 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Branched chain keto acid dehydrogenase E1 subunit beta. | 0.946 |
DLAT | ENSAPLP00000024157 | ENSAPLP00000005029 | ENSAPLP00000024157 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.996 |
DLAT | GCSH | ENSAPLP00000005029 | ENSAPLP00000029441 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.807 |
DLAT | LIAS | ENSAPLP00000005029 | ENSAPLP00000011673 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.632 |
DLAT | LIPT1 | ENSAPLP00000005029 | ENSAPLP00000001416 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Lipoyltransferase 1. | 0.882 |