TSHR protein (Anas platyrhynchos) - STRING interaction network

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TSHR

Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (765 aa)

Predicted Functional Partners:

TSHB

0.996

GPHB5

0.969

GNAS

0.950

GNB3

0.926

GNB4

0.926

GNG2

0.926

GNB1

0.925

TPO

0.924

GNG4

0.923

GNB5

0.922

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GNAS	GNB1	ENSAPLP00000015255	ENSAPLP00000010816	GNAS complex locus.	G protein subunit beta 1.	0.932
GNAS	GNB3	ENSAPLP00000015255	ENSAPLP00000002795	GNAS complex locus.	G protein subunit beta 3.	0.854
GNAS	GNB4	ENSAPLP00000015255	ENSAPLP00000012022	GNAS complex locus.	G protein subunit beta 4.	0.882
GNAS	GNB5	ENSAPLP00000015255	ENSAPLP00000016983	GNAS complex locus.	G protein subunit beta 5.	0.719
GNAS	GNG2	ENSAPLP00000015255	ENSAPLP00000025803	GNAS complex locus.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.826
GNAS	GNG4	ENSAPLP00000015255	ENSAPLP00000005927	GNAS complex locus.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.826
GNAS	TSHR	ENSAPLP00000015255	ENSAPLP00000001436	GNAS complex locus.	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.	0.950
GNB1	GNAS	ENSAPLP00000010816	ENSAPLP00000015255	G protein subunit beta 1.	GNAS complex locus.	0.932
GNB1	GNB3	ENSAPLP00000010816	ENSAPLP00000002795	G protein subunit beta 1.	G protein subunit beta 3.	0.475
GNB1	GNB5	ENSAPLP00000010816	ENSAPLP00000016983	G protein subunit beta 1.	G protein subunit beta 5.	0.448
GNB1	GNG2	ENSAPLP00000010816	ENSAPLP00000025803	G protein subunit beta 1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.905
GNB1	GNG4	ENSAPLP00000010816	ENSAPLP00000005927	G protein subunit beta 1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.905
GNB1	TSHB	ENSAPLP00000010816	ENSAPLP00000007376	G protein subunit beta 1.	Thyroid stimulating hormone subunit beta.	0.587
GNB1	TSHR	ENSAPLP00000010816	ENSAPLP00000001436	G protein subunit beta 1.	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.	0.925
GNB3	GNAS	ENSAPLP00000002795	ENSAPLP00000015255	G protein subunit beta 3.	GNAS complex locus.	0.854
GNB3	GNB1	ENSAPLP00000002795	ENSAPLP00000010816	G protein subunit beta 3.	G protein subunit beta 1.	0.475
GNB3	GNB4	ENSAPLP00000002795	ENSAPLP00000012022	G protein subunit beta 3.	G protein subunit beta 4.	0.477
GNB3	GNB5	ENSAPLP00000002795	ENSAPLP00000016983	G protein subunit beta 3.	G protein subunit beta 5.	0.414
GNB3	GNG2	ENSAPLP00000002795	ENSAPLP00000025803	G protein subunit beta 3.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.892
GNB3	GNG4	ENSAPLP00000002795	ENSAPLP00000005927	G protein subunit beta 3.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.892

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