STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PGAP1GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi. (1009 aa)    
Predicted Functional Partners:
MPPE1
Metallophosphoesterase 1.
    
 0.961
PIGK
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
    
 0.953
PIGS
Phosphatidylinositol glycan anchor biosynthesis class S.
     
 0.945
PIGT
Phosphatidylinositol glycan anchor biosynthesis class T.
     
 0.942
PIGU
Phosphatidylinositol glycan anchor biosynthesis class U.
     
 0.937
TMED10
Transmembrane p24 trafficking protein 10.
    
 
 0.797
PIGC
Phosphatidylinositol glycan anchor biosynthesis class C.
      
 0.758
PIGG
Phosphatidylinositol glycan anchor biosynthesis class G.
   
 
 0.730
TLE4
Uncharacterized protein.
      
 0.690
GANAB
Glucosidase II alpha subunit; Belongs to the glycosyl hydrolase 31 family.
    
   0.684
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.