| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACO1 | ACO2 | ENSAPLP00000015419 | ENSAPLP00000026786 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | 0.934 |
| ACO1 | CS | ENSAPLP00000015419 | ENSAPLP00000032070 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Citrate synthase; Belongs to the citrate synthase family. | 0.996 |
| ACO1 | ENSAPLP00000030507 | ENSAPLP00000015419 | ENSAPLP00000030507 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Iso_dh domain-containing protein. | 0.664 |
| ACO1 | ENSAPLP00000031213 | ENSAPLP00000015419 | ENSAPLP00000031213 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Iso_dh domain-containing protein. | 0.664 |
| ACO1 | IDH1 | ENSAPLP00000015419 | ENSAPLP00000014674 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.992 |
| ACO1 | IDH2 | ENSAPLP00000015419 | ENSAPLP00000021667 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.992 |
| ACO1 | IDH3A | ENSAPLP00000015419 | ENSAPLP00000001511 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. | 0.971 |
| ACO1 | OGDH | ENSAPLP00000015419 | ENSAPLP00000016172 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Oxoglutarate dehydrogenase. | 0.587 |
| ACO1 | OGDHL | ENSAPLP00000015419 | ENSAPLP00000012351 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Oxoglutarate dehydrogenase like. | 0.574 |
| ACO1 | SUCLA2 | ENSAPLP00000015419 | ENSAPLP00000008130 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.733 |
| ACO2 | ACO1 | ENSAPLP00000026786 | ENSAPLP00000015419 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | 0.934 |
| ACO2 | CS | ENSAPLP00000026786 | ENSAPLP00000032070 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Citrate synthase; Belongs to the citrate synthase family. | 0.999 |
| ACO2 | ENSAPLP00000030507 | ENSAPLP00000026786 | ENSAPLP00000030507 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Iso_dh domain-containing protein. | 0.920 |
| ACO2 | ENSAPLP00000031213 | ENSAPLP00000026786 | ENSAPLP00000031213 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Iso_dh domain-containing protein. | 0.920 |
| ACO2 | IDH1 | ENSAPLP00000026786 | ENSAPLP00000014674 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.992 |
| ACO2 | IDH2 | ENSAPLP00000026786 | ENSAPLP00000021667 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.993 |
| ACO2 | IDH3A | ENSAPLP00000026786 | ENSAPLP00000001511 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. | 0.998 |
| ACO2 | OGDH | ENSAPLP00000026786 | ENSAPLP00000016172 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Oxoglutarate dehydrogenase. | 0.926 |
| ACO2 | OGDHL | ENSAPLP00000026786 | ENSAPLP00000012351 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Oxoglutarate dehydrogenase like. | 0.926 |
| ACO2 | SUCLA2 | ENSAPLP00000026786 | ENSAPLP00000008130 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.910 |