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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MC5RMelanocortin 5 receptor. (325 aa)    
Predicted Functional Partners:
POMC
Proopiomelanocortin.
    
 0.987
MRAP2
Melanocortin 2 receptor accessory protein 2.
    
 
 0.805
CMC4
C-X9-C motif containing 4.
      
 0.697
NPY1R
Neuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family.
      
 0.667
ORAI1
ORAI calcium release-activated calcium modulator 1.
    
 
 0.631
DYRK4
Dual specificity tyrosine phosphorylation regulated kinase 4.
      
 0.547
FAM237A
Family with sequence similarity 237 member A.
     
 0.545
AGRP
Agouti domain-containing protein.
    
 
 0.543
TRIB2
Tribbles pseudokinase 2.
    
 
 0.458
APOD
Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family.
      
 0.457
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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