STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MOV10L1Mov10 like RISC complex RNA helicase 1. (1068 aa)    
Predicted Functional Partners:
PIWIL2
Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family.
   
 0.777
PIWIL1
Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family.
   
 0.755
ASZ1
ANK_REP_REGION domain-containing protein.
   
 0.753
TDRD1
Tudor domain containing 1.
   
 0.708
PLD6
Phospholipase D family member 6.
    
 
 0.704
TDRD12
Uncharacterized protein.
    
 0.702
TDRD9
Tudor domain containing 9.
    
 0.677
UPF1
UPF1 RNA helicase and ATPase.
   
 
 0.656
AKAP12
A-kinase anchoring protein 12.
      
 0.655
AGO2
Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]
    
 0.642
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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