Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
HIC2HIC ZBTB transcriptional repressor 2. (570 aa)    
Predicted Functional Partners:
SIRT1
Sirtuin 1.
    
 
 0.758
NUDCD1
NudC domain containing 1.
    
   0.756
CTBP2
C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 
 0.660
CTBP1
C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 
 0.660
MPP5
Membrane palmitoylated protein 5; Belongs to the MAGUK family.
    
 0.569
FNDC4
Fibronectin type III domain containing 4.
      
 0.545
UBE2I
Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.544
ZBTB8A
Zinc finger and BTB domain containing 8A.
    
   0.535
ENSAPLP00000026629
Uncharacterized protein.
    
   0.535
U3IK86_ANAPP
PH domain-containing protein.
     
 0.507
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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