| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACMSD | SENP8 | ENSAPLP00000020077 | ENSAPLP00000001802 | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. | SUMO peptidase family member, NEDD8 specific. | 0.810 |
| ACO1 | ACO2 | ENSAPLP00000015419 | ENSAPLP00000026786 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | 0.934 |
| ACO1 | CUL1 | ENSAPLP00000015419 | ENSAPLP00000020847 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Cullin 1; Belongs to the cullin family. | 0.589 |
| ACO1 | IREB2 | ENSAPLP00000015419 | ENSAPLP00000019949 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. | 0.573 |
| ACO1 | SENP8 | ENSAPLP00000015419 | ENSAPLP00000001802 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | SUMO peptidase family member, NEDD8 specific. | 0.770 |
| ACO2 | ACO1 | ENSAPLP00000026786 | ENSAPLP00000015419 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | 0.934 |
| ACO2 | SENP8 | ENSAPLP00000026786 | ENSAPLP00000001802 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | SUMO peptidase family member, NEDD8 specific. | 0.770 |
| CUL1 | ACO1 | ENSAPLP00000020847 | ENSAPLP00000015419 | Cullin 1; Belongs to the cullin family. | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | 0.589 |
| CUL1 | IREB2 | ENSAPLP00000020847 | ENSAPLP00000019949 | Cullin 1; Belongs to the cullin family. | Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. | 0.652 |
| CUL1 | PSMD7 | ENSAPLP00000020847 | ENSAPLP00000008572 | Cullin 1; Belongs to the cullin family. | Proteasome 26S subunit, non-ATPase 7. | 0.687 |
| CUL1 | SENP8 | ENSAPLP00000020847 | ENSAPLP00000001802 | Cullin 1; Belongs to the cullin family. | SUMO peptidase family member, NEDD8 specific. | 0.878 |
| IREB2 | ACO1 | ENSAPLP00000019949 | ENSAPLP00000015419 | Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | 0.573 |
| IREB2 | CUL1 | ENSAPLP00000019949 | ENSAPLP00000020847 | Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. | Cullin 1; Belongs to the cullin family. | 0.652 |
| IREB2 | SENP8 | ENSAPLP00000019949 | ENSAPLP00000001802 | Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. | SUMO peptidase family member, NEDD8 specific. | 0.770 |
| PIGL | SENP8 | ENSAPLP00000026185 | ENSAPLP00000001802 | Phosphatidylinositol glycan anchor biosynthesis class L. | SUMO peptidase family member, NEDD8 specific. | 0.808 |
| PSMD7 | CUL1 | ENSAPLP00000008572 | ENSAPLP00000020847 | Proteasome 26S subunit, non-ATPase 7. | Cullin 1; Belongs to the cullin family. | 0.687 |
| PSMD7 | SENP8 | ENSAPLP00000008572 | ENSAPLP00000001802 | Proteasome 26S subunit, non-ATPase 7. | SUMO peptidase family member, NEDD8 specific. | 0.704 |
| PSMD7 | UCHL1 | ENSAPLP00000008572 | ENSAPLP00000018961 | Proteasome 26S subunit, non-ATPase 7. | Ubiquitin carboxyl-terminal hydrolase. | 0.604 |
| PSMD7 | UCHL3 | ENSAPLP00000008572 | ENSAPLP00000018779 | Proteasome 26S subunit, non-ATPase 7. | Ubiquitin carboxyl-terminal hydrolase. | 0.604 |
| PSTPIP2 | SENP8 | ENSAPLP00000031695 | ENSAPLP00000001802 | Proline-serine-threonine phosphatase interacting protein 2. | SUMO peptidase family member, NEDD8 specific. | 0.749 |