Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (575 aa)    
Predicted Functional Partners:
PANX1
Pannexin; Structural component of the gap junctions and the hemichannels.
     
 0.883
ENSAPLP00000022103
Brix domain-containing protein.
      
 0.665
P2RY4
Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family.
     
 0.597
P2RX5
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
   
  0.596
P2RY1
Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family.
      
 0.581
P2RY6
Pyrimidinergic receptor P2Y6.
      
 0.548
ENSAPLP00000020265
Uncharacterized protein.
      
 0.548
GPR132
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.449
TLR4
Toll like receptor 4.
   
  
 0.427
TRANK1
Tetratricopeptide repeat and ankyrin repeat containing 1.
      
 0.427
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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