Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DEPDC1DEP domain containing 1. (812 aa)    
Predicted Functional Partners:
RPE65
Retinoid isomerohydrolase RPE65.
 
      0.607
CCNB2
Cyclin B2; Belongs to the cyclin family.
   
  
 0.599
DLGAP5
DLG associated protein 5.
   
  
 0.587
ENSAPLP00000029215
Uncharacterized protein.
     
 0.555
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 0.544
U3IFA0_ANAPP
Rho-GAP domain-containing protein.
   
 
 0.530
ASPM
Abnormal spindle microtubule assembly.
   
  
 0.525
C2H18orf63
DUF4708 domain-containing protein.
   
  
 0.506
KIF14
Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.502
RLBP1
Retinaldehyde binding protein 1.
   
  
 0.489
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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