Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZAP70Tyrosine-protein kinase. (607 aa)    
Predicted Functional Partners:
CD247
CD247 molecule.
   
 0.997
CD3E
CD3e molecule.
   
 0.994
LCK
Tyrosine-protein kinase.
  
0.922
U3ISR2_ANAPP
Ig_4 domain-containing protein.
   
 0.918
ENSAPLP00000024741
Protein kinase domain-containing protein.
   
 0.906
CBL
Cbl proto-oncogene.
    
 0.894
CRK
CRK proto-oncogene, adaptor protein.
    
 0.890
GRB2
Growth factor receptor bound protein 2.
   
0.875
BLNK
B cell linker.
   
 0.868
CBLB
Cbl proto-oncogene B.
    
 0.849
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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