HMOX2 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

HMOX2

Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (312 aa)

Predicted Functional Partners:

BLVRA

0.963

FECH

0.940

BLVRB

0.936

FXN

0.926

ENSAPLP00000028813

0.924

HEPH

0.909

CP

0.909

HEPHL1

0.909

COX10

0.904

HMOX1

0.902

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BLVRA	BLVRB	ENSAPLP00000003318	ENSAPLP00000024436	Biliverdin reductase A.	Uncharacterized protein.	0.988
BLVRA	FECH	ENSAPLP00000003318	ENSAPLP00000015115	Biliverdin reductase A.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	0.699
BLVRA	HEPH	ENSAPLP00000003318	ENSAPLP00000004961	Biliverdin reductase A.	Hephaestin; Belongs to the multicopper oxidase family.	0.532
BLVRA	HMOX1	ENSAPLP00000003318	ENSAPLP00000007923	Biliverdin reductase A.	Heme oxygenase 1.	0.968
BLVRA	HMOX2	ENSAPLP00000003318	ENSAPLP00000001913	Biliverdin reductase A.	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.	0.963
BLVRB	BLVRA	ENSAPLP00000024436	ENSAPLP00000003318	Uncharacterized protein.	Biliverdin reductase A.	0.988
BLVRB	FECH	ENSAPLP00000024436	ENSAPLP00000015115	Uncharacterized protein.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	0.524
BLVRB	HMOX1	ENSAPLP00000024436	ENSAPLP00000007923	Uncharacterized protein.	Heme oxygenase 1.	0.936
BLVRB	HMOX2	ENSAPLP00000024436	ENSAPLP00000001913	Uncharacterized protein.	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.	0.936
COX10	FECH	ENSAPLP00000024073	ENSAPLP00000015115	Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	0.952
COX10	HMOX1	ENSAPLP00000024073	ENSAPLP00000007923	Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family.	Heme oxygenase 1.	0.904
COX10	HMOX2	ENSAPLP00000024073	ENSAPLP00000001913	Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family.	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.	0.904
CP	ENSAPLP00000028813	ENSAPLP00000007495	ENSAPLP00000028813	Ceruloplasmin; Belongs to the multicopper oxidase family.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.912
CP	FECH	ENSAPLP00000007495	ENSAPLP00000015115	Ceruloplasmin; Belongs to the multicopper oxidase family.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	0.919
CP	FXN	ENSAPLP00000007495	ENSAPLP00000029650	Ceruloplasmin; Belongs to the multicopper oxidase family.	Frataxin.	0.919
CP	HEPH	ENSAPLP00000007495	ENSAPLP00000004961	Ceruloplasmin; Belongs to the multicopper oxidase family.	Hephaestin; Belongs to the multicopper oxidase family.	0.902
CP	HEPHL1	ENSAPLP00000007495	ENSAPLP00000015603	Ceruloplasmin; Belongs to the multicopper oxidase family.	Hephaestin like 1; Belongs to the multicopper oxidase family.	0.902
CP	HMOX1	ENSAPLP00000007495	ENSAPLP00000007923	Ceruloplasmin; Belongs to the multicopper oxidase family.	Heme oxygenase 1.	0.909
CP	HMOX2	ENSAPLP00000007495	ENSAPLP00000001913	Ceruloplasmin; Belongs to the multicopper oxidase family.	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.	0.909
ENSAPLP00000028813	CP	ENSAPLP00000028813	ENSAPLP00000007495	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ceruloplasmin; Belongs to the multicopper oxidase family.	0.912

page 1 of 4

Server load: low (32%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About