Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IGSF21Immunoglobin superfamily member 21. (434 aa)    
Predicted Functional Partners:
AURKA
Aurora kinase A; Belongs to the protein kinase superfamily.
   
 0.745
VPS13D
Vacuolar protein sorting 13 homolog D.
      
 0.641
LRMDA
Leucine rich melanocyte differentiation associated.
    
 0.633
LDLRAP1
Low density lipoprotein receptor adaptor protein 1.
     
 0.621
ADGRL2
Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.
    
 0.620
RRM2
Ribonucleotide reductase regulatory subunit M2.
   
 
 0.602
TNFAIP6
TNF alpha induced protein 6.
    
 0.590
CLVS2
Clavesin 2.
   
 0.579
CLVS1
Clavesin 1.
   
 0.579
PARK7
Parkinsonism associated deglycase.
   
 0.576
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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