STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
METAP1DMethionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). (338 aa)    
Predicted Functional Partners:
ENSAPLP00000024321
Rieske domain-containing protein.
  
 
 0.880
IYD
Iodotyrosine deiodinase.
  
 
 0.862
FDX1
Ferredoxin 1.
  
 
 0.804
PDF
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family.
     
 0.753
MTFMT
Mitochondrial methionyl-tRNA formyltransferase.
      
 0.684
CRYL1
Crystallin lambda 1.
  
 
 0.672
HADH
Hydroxyacyl-CoA dehydrogenase.
  
 
 0.672
H6PD
Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.
  
  
 0.671
METAP2
Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
      
 0.611
TMEM161A
Transmembrane protein 161A.
      
 0.611
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.