Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
HNF1AHomeobox domain-containing protein. (634 aa)    
Predicted Functional Partners:
HNF1B
HNF1 homeobox B.
   
 
 0.951
PCBD2
Pterin-4 alpha-carbinolamine dehydratase 2.
    
 
 0.929
PCBD1
Pterin-4 alpha-carbinolamine dehydratase 1.
    
 
 0.918
HNF4A
Hepatocyte nuclear factor 4 alpha.
   
 0.784
SLC2A2
Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
   
 
 0.759
CREBBP
CREB binding protein.
    
 
 0.696
PDX1
Homeobox domain-containing protein.
   
  
 0.628
DYRK1A
Dual specificity tyrosine phosphorylation regulated kinase 1A.
    
 
 0.615
ABCC8
ATP binding cassette subfamily C member 8.
   
  
 0.607
PTF1A
Pancreas associated transcription factor 1a.
     
 0.602
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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