Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
TSPAN12Tetraspanin. (305 aa)    
Predicted Functional Partners:
FZD4
Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.
   
 
 0.858
ENSAPLP00000017710
Uncharacterized protein.
     
 0.853
NDP
Norrin cystine knot growth factor NDP.
  
 
 0.748
RECK
Reversion inducing cysteine rich protein with kazal motifs.
      
 0.720
U3IYG0_ANAPP
CTCK domain-containing protein.
    
 0.680
ARHGAP31
Rho GTPase activating protein 31.
      
 0.672
LGR4
Leucine rich repeat containing G protein-coupled receptor 4.
     
 0.652
KIF11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.631
LRP5
Uncharacterized protein.
     
 0.626
JAG1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
     
 0.609
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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