Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
INCENPINCENP_N domain-containing protein. (534 aa)    
Predicted Functional Partners:
CDCA8
Cell division cycle associated 8.
   
 0.991
U3J5Y8_ANAPP
Uncharacterized protein.
   
 0.983
AURKA
Aurora kinase A; Belongs to the protein kinase superfamily.
   
 0.932
ENSAPLP00000024558
Protein kinase domain-containing protein.
   
 0.932
PLK1
Serine/threonine-protein kinase PLK.
   
 0.885
NDC80
NDC80 kinetochore complex component.
   
  
 0.882
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.853
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.850
BUB1B
Uncharacterized protein.
   
 0.839
U3IRE9_ANAPP
Nbl1_Borealin_N domain-containing protein.
    
 0.829
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (10%) [HD]