SENP7 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

SENP7

SUMO specific peptidase 7. (1051 aa)

Predicted Functional Partners:

SUMO1

0.835

SETDB2

0.822

SUMO2

0.801

ENSAPLP00000029099

0.801

SENP2

0.780

SENP1

0.780

UBA2

0.707

CBX1

0.697

CBX5

0.697

PIAS4

0.674

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBX1	SENP7	ENSAPLP00000022072	ENSAPLP00000002124	Chromobox 1.	SUMO specific peptidase 7.	0.697
CBX1	SETDB2	ENSAPLP00000022072	ENSAPLP00000008739	Chromobox 1.	SET domain bifurcated histone lysine methyltransferase 2.	0.498
CBX5	SENP7	ENSAPLP00000025675	ENSAPLP00000002124	Chromobox 5.	SUMO specific peptidase 7.	0.697
CBX5	SETDB2	ENSAPLP00000025675	ENSAPLP00000008739	Chromobox 5.	SET domain bifurcated histone lysine methyltransferase 2.	0.498
ENSAPLP00000029099	PIAS4	ENSAPLP00000029099	ENSAPLP00000010609	Ubiquitin-like domain-containing protein.	Protein inhibitor of activated STAT 4.	0.917
ENSAPLP00000029099	SENP1	ENSAPLP00000029099	ENSAPLP00000010434	Ubiquitin-like domain-containing protein.	SUMO specific peptidase 1.	0.906
ENSAPLP00000029099	SENP2	ENSAPLP00000029099	ENSAPLP00000002598	Ubiquitin-like domain-containing protein.	ULP_PROTEASE domain-containing protein.	0.856
ENSAPLP00000029099	SENP7	ENSAPLP00000029099	ENSAPLP00000002124	Ubiquitin-like domain-containing protein.	SUMO specific peptidase 7.	0.801
ENSAPLP00000029099	SETDB2	ENSAPLP00000029099	ENSAPLP00000008739	Ubiquitin-like domain-containing protein.	SET domain bifurcated histone lysine methyltransferase 2.	0.425
ENSAPLP00000029099	SUMO1	ENSAPLP00000029099	ENSAPLP00000022646	Ubiquitin-like domain-containing protein.	Small ubiquitin like modifier 1.	0.741
ENSAPLP00000029099	UBA2	ENSAPLP00000029099	ENSAPLP00000010917	Ubiquitin-like domain-containing protein.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.961
PIAS4	ENSAPLP00000029099	ENSAPLP00000010609	ENSAPLP00000029099	Protein inhibitor of activated STAT 4.	Ubiquitin-like domain-containing protein.	0.917
PIAS4	SENP1	ENSAPLP00000010609	ENSAPLP00000010434	Protein inhibitor of activated STAT 4.	SUMO specific peptidase 1.	0.744
PIAS4	SENP2	ENSAPLP00000010609	ENSAPLP00000002598	Protein inhibitor of activated STAT 4.	ULP_PROTEASE domain-containing protein.	0.434
PIAS4	SENP7	ENSAPLP00000010609	ENSAPLP00000002124	Protein inhibitor of activated STAT 4.	SUMO specific peptidase 7.	0.674
PIAS4	SUMO1	ENSAPLP00000010609	ENSAPLP00000022646	Protein inhibitor of activated STAT 4.	Small ubiquitin like modifier 1.	0.965
PIAS4	SUMO2	ENSAPLP00000010609	ENSAPLP00000006410	Protein inhibitor of activated STAT 4.	Small ubiquitin-related modifier.	0.935
PIAS4	UBA2	ENSAPLP00000010609	ENSAPLP00000010917	Protein inhibitor of activated STAT 4.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.612
SENP1	ENSAPLP00000029099	ENSAPLP00000010434	ENSAPLP00000029099	SUMO specific peptidase 1.	Ubiquitin-like domain-containing protein.	0.906
SENP1	PIAS4	ENSAPLP00000010434	ENSAPLP00000010609	SUMO specific peptidase 1.	Protein inhibitor of activated STAT 4.	0.744