Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
HELLSHelicase, lymphoid specific. (778 aa)    
Predicted Functional Partners:
CHD2
DUF4208 domain-containing protein.
 
 
 
 0.869
U3I3F9_ANAPP
POU domain protein.
    
 
 0.790
HESX1
HESX homeobox 1.
    
 
 0.752
POLE3
CBFD_NFYB_HMF domain-containing protein.
    
 0.751
RAD51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
  
 0.739
ENSAPLP00000028245
Uncharacterized protein.
   
 0.738
TTK
TTK protein kinase.
   
 
 0.718
KAT2B
Lysine acetyltransferase 2B.
    
 0.708
MYSM1
Myb like, SWIRM and MPN domains 1.
   
 0.693
RAD52
RAD52 homolog, DNA repair protein.
    
 
 0.682
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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