STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4136 aa)    
Predicted Functional Partners:
XRCC6
X-ray repair cross complementing 6.
    
 0.999
LIG4
DNA ligase.
   
 0.993
XRCC5
X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.
   
 0.989
DCLRE1C
DNA cross-link repair 1C.
    
 0.985
RNF144A
RBR-type E3 ubiquitin transferase.
    
 0.920
RICTOR
RPTOR independent companion of MTOR complex 2.
   
 0.907
MLST8
MTOR associated protein, LST8 homolog.
    
 0.906
MAPKAP1
MAPK associated protein 1.
    
 0.904
BRCA1
BRCA1 DNA repair associated.
   
 0.865
LYN
Tyrosine-protein kinase.
    
 0.855
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.