Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PKD2Polycystin 2, transient receptor potential cation channel. (715 aa)    
Predicted Functional Partners:
PKD1
PLAT domain-containing protein.
   
 0.998
TRPC1
Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.818
NUDT9
Nudix hydrolase 9.
      
 0.703
PKHD1
PKHD1 ciliary IPT domain containing fibrocystin/polyductin.
      
 0.695
EXOC5
Exocyst complex component 5.
     
 0.679
RASGEF1B
RasGEF domain family member 1B.
   
  
 0.667
IFT140
Intraflagellar transport 140.
      
 0.664
EXOC2
Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.
     
  0.647
ENSAPLP00000032763
PLAT domain-containing protein.
   
 0.638
U3I5C9_ANAPP
Uncharacterized protein.
 
    
 0.631
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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