Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HIF1AHypoxia inducible factor 1 subunit alpha. (770 aa)    
Predicted Functional Partners:
ARNT
Aryl hydrocarbon receptor nuclear translocator.
   
0.989
HIF1AN
Hypoxia inducible factor 1 subunit alpha inhibitor.
    
 0.973
U3I7D3_ANAPP
Uncharacterized protein.
    
 0.958
ELOC
Skp1_POZ domain-containing protein; Belongs to the SKP1 family.
    
 0.947
ENSAPLP00000023149
Uncharacterized protein.
    
 0.942
CUL2
Cullin 2; Belongs to the cullin family.
    
 0.940
EP300
E1A binding protein p300.
    
 0.939
STAT3
Signal transducer and activator of transcription.
    
 0.936
CREBBP
CREB binding protein.
    
 0.933
CTNNB1
Catenin beta 1.
   
 0.906
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.