FMO3 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

FMO3

Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)

Predicted Functional Partners:

GAD1

0.906

GAD2

0.906

GADL1

0.906

GGT5

0.903

GGT1

0.903

GGT7

0.903

ENSAPLP00000017305

0.900

EPHX1

0.646

GPC3

0.487

STK32C

0.455

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPLP00000017305	FMO3	ENSAPLP00000017305	ENSAPLP00000002233	BAAT_C domain-containing protein.	Dimethylaniline monooxygenase [N-oxide-forming].	0.900
ENSAPLP00000017305	GAD1	ENSAPLP00000017305	ENSAPLP00000004685	BAAT_C domain-containing protein.	Glutamate decarboxylase 1.	0.902
ENSAPLP00000017305	GAD2	ENSAPLP00000017305	ENSAPLP00000006672	BAAT_C domain-containing protein.	Glutamate decarboxylase 2.	0.901
ENSAPLP00000017305	GADL1	ENSAPLP00000017305	ENSAPLP00000032882	BAAT_C domain-containing protein.	Glutamate decarboxylase like 1.	0.908
ENSAPLP00000017305	GGT1	ENSAPLP00000017305	ENSAPLP00000007860	BAAT_C domain-containing protein.	Uncharacterized protein.	0.900
ENSAPLP00000017305	GGT5	ENSAPLP00000017305	ENSAPLP00000007665	BAAT_C domain-containing protein.	Uncharacterized protein.	0.900
ENSAPLP00000017305	GGT7	ENSAPLP00000017305	ENSAPLP00000013231	BAAT_C domain-containing protein.	Gamma-glutamyltransferase 7.	0.900
EPHX1	FMO3	ENSAPLP00000015248	ENSAPLP00000002233	Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.	Dimethylaniline monooxygenase [N-oxide-forming].	0.646
FMO3	ENSAPLP00000017305	ENSAPLP00000002233	ENSAPLP00000017305	Dimethylaniline monooxygenase [N-oxide-forming].	BAAT_C domain-containing protein.	0.900
FMO3	EPHX1	ENSAPLP00000002233	ENSAPLP00000015248	Dimethylaniline monooxygenase [N-oxide-forming].	Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.	0.646
FMO3	GAD1	ENSAPLP00000002233	ENSAPLP00000004685	Dimethylaniline monooxygenase [N-oxide-forming].	Glutamate decarboxylase 1.	0.906
FMO3	GAD2	ENSAPLP00000002233	ENSAPLP00000006672	Dimethylaniline monooxygenase [N-oxide-forming].	Glutamate decarboxylase 2.	0.906
FMO3	GADL1	ENSAPLP00000002233	ENSAPLP00000032882	Dimethylaniline monooxygenase [N-oxide-forming].	Glutamate decarboxylase like 1.	0.906
FMO3	GGT1	ENSAPLP00000002233	ENSAPLP00000007860	Dimethylaniline monooxygenase [N-oxide-forming].	Uncharacterized protein.	0.903
FMO3	GGT5	ENSAPLP00000002233	ENSAPLP00000007665	Dimethylaniline monooxygenase [N-oxide-forming].	Uncharacterized protein.	0.903
FMO3	GGT7	ENSAPLP00000002233	ENSAPLP00000013231	Dimethylaniline monooxygenase [N-oxide-forming].	Gamma-glutamyltransferase 7.	0.903
FMO3	GPC3	ENSAPLP00000002233	ENSAPLP00000018003	Dimethylaniline monooxygenase [N-oxide-forming].	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.487
FMO3	STK32C	ENSAPLP00000002233	ENSAPLP00000004551	Dimethylaniline monooxygenase [N-oxide-forming].	Serine/threonine kinase 32C.	0.455
GAD1	ENSAPLP00000017305	ENSAPLP00000004685	ENSAPLP00000017305	Glutamate decarboxylase 1.	BAAT_C domain-containing protein.	0.902
GAD1	FMO3	ENSAPLP00000004685	ENSAPLP00000002233	Glutamate decarboxylase 1.	Dimethylaniline monooxygenase [N-oxide-forming].	0.906