| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| COMT | CYP1B1 | ENSAPLP00000002241 | ENSAPLP00000000825 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.938 |
| COMT | DBH | ENSAPLP00000002241 | ENSAPLP00000006776 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Dopamine beta-hydroxylase. | 0.956 |
| COMT | DDC | ENSAPLP00000002241 | ENSAPLP00000002755 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Dopa decarboxylase. | 0.957 |
| COMT | ENSAPLP00000017423 | ENSAPLP00000002241 | ENSAPLP00000017423 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. | 0.920 |
| COMT | ENSAPLP00000017633 | ENSAPLP00000002241 | ENSAPLP00000017633 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Uncharacterized protein. | 0.905 |
| COMT | ENSAPLP00000022256 | ENSAPLP00000002241 | ENSAPLP00000022256 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.922 |
| COMT | ENSAPLP00000026493 | ENSAPLP00000002241 | ENSAPLP00000026493 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.920 |
| COMT | MAOA | ENSAPLP00000002241 | ENSAPLP00000013107 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Amine oxidase. | 0.979 |
| COMT | PNMT | ENSAPLP00000002241 | ENSAPLP00000025136 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Phenylethanolamine N-methyltransferase. | 0.945 |
| COMT | U3ITZ1_ANAPP | ENSAPLP00000002241 | ENSAPLP00000010714 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.922 |
| CYP1B1 | COMT | ENSAPLP00000000825 | ENSAPLP00000002241 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | 0.938 |
| CYP1B1 | ENSAPLP00000017633 | ENSAPLP00000000825 | ENSAPLP00000017633 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | Uncharacterized protein. | 0.904 |
| CYP1B1 | ENSAPLP00000022256 | ENSAPLP00000000825 | ENSAPLP00000022256 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.930 |
| CYP1B1 | U3ITZ1_ANAPP | ENSAPLP00000000825 | ENSAPLP00000010714 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.930 |
| DBH | COMT | ENSAPLP00000006776 | ENSAPLP00000002241 | Dopamine beta-hydroxylase. | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | 0.956 |
| DBH | DDC | ENSAPLP00000006776 | ENSAPLP00000002755 | Dopamine beta-hydroxylase. | Dopa decarboxylase. | 0.965 |
| DBH | MAOA | ENSAPLP00000006776 | ENSAPLP00000013107 | Dopamine beta-hydroxylase. | Amine oxidase. | 0.959 |
| DBH | PNMT | ENSAPLP00000006776 | ENSAPLP00000025136 | Dopamine beta-hydroxylase. | Phenylethanolamine N-methyltransferase. | 0.986 |
| DDC | COMT | ENSAPLP00000002755 | ENSAPLP00000002241 | Dopa decarboxylase. | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | 0.957 |
| DDC | DBH | ENSAPLP00000002755 | ENSAPLP00000006776 | Dopa decarboxylase. | Dopamine beta-hydroxylase. | 0.965 |