TFRC protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

TFRC

Transferrin receptor. (775 aa)

Predicted Functional Partners:

TF

0.979

YWHAZ

0.873

PGK1

0.873

SDHA

0.822

MELTF

0.808

ENSAPLP00000020806

0.808

OPTN

0.779

HJV

0.779

RPL4

0.767

ENSAPLP00000028813

0.765

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPLP00000020806	TFRC	ENSAPLP00000020806	ENSAPLP00000002263	Transferrin-like domain-containing protein.	Transferrin receptor.	0.808
ENSAPLP00000028813	TFRC	ENSAPLP00000028813	ENSAPLP00000002263	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Transferrin receptor.	0.765
HJV	TFRC	ENSAPLP00000017107	ENSAPLP00000002263	Hemojuvelin BMP co-receptor.	Transferrin receptor.	0.779
MELTF	TFRC	ENSAPLP00000005744	ENSAPLP00000002263	Ovotransferrin; Belongs to the transferrin family.	Transferrin receptor.	0.808
OPTN	TFRC	ENSAPLP00000004235	ENSAPLP00000002263	Optineurin.	Transferrin receptor.	0.779
PGK1	RPL4	ENSAPLP00000022405	ENSAPLP00000015754	Phosphoglycerate kinase.	Ribosomal protein L4.	0.756
PGK1	SDHA	ENSAPLP00000022405	ENSAPLP00000006678	Phosphoglycerate kinase.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.569
PGK1	TFRC	ENSAPLP00000022405	ENSAPLP00000002263	Phosphoglycerate kinase.	Transferrin receptor.	0.873
PGK1	YWHAZ	ENSAPLP00000022405	ENSAPLP00000002091	Phosphoglycerate kinase.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family.	0.782
RPL4	PGK1	ENSAPLP00000015754	ENSAPLP00000022405	Ribosomal protein L4.	Phosphoglycerate kinase.	0.756
RPL4	SDHA	ENSAPLP00000015754	ENSAPLP00000006678	Ribosomal protein L4.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.655
RPL4	TFRC	ENSAPLP00000015754	ENSAPLP00000002263	Ribosomal protein L4.	Transferrin receptor.	0.767
RPL4	YWHAZ	ENSAPLP00000015754	ENSAPLP00000002091	Ribosomal protein L4.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family.	0.663
SDHA	PGK1	ENSAPLP00000006678	ENSAPLP00000022405	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	Phosphoglycerate kinase.	0.569
SDHA	RPL4	ENSAPLP00000006678	ENSAPLP00000015754	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	Ribosomal protein L4.	0.655
SDHA	TFRC	ENSAPLP00000006678	ENSAPLP00000002263	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	Transferrin receptor.	0.822
SDHA	YWHAZ	ENSAPLP00000006678	ENSAPLP00000002091	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family.	0.731
TF	TFRC	ENSAPLP00000027562	ENSAPLP00000002263	Ovotransferrin; Belongs to the transferrin family.	Transferrin receptor.	0.979
TFRC	ENSAPLP00000020806	ENSAPLP00000002263	ENSAPLP00000020806	Transferrin receptor.	Transferrin-like domain-containing protein.	0.808
TFRC	ENSAPLP00000028813	ENSAPLP00000002263	ENSAPLP00000028813	Transferrin receptor.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.765