STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMPDL3BSphingomyelin phosphodiesterase acid like 3B. (593 aa)    
Predicted Functional Partners:
MRPL35
Mitochondrial ribosomal protein L35.
      
 0.748
MRPS11
Mitochondrial ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family.
      
 0.747
BZW2
Basic leucine zipper and W2 domains 2.
      
 0.684
MTRF1
Mitochondrial translation release factor 1.
      
 0.635
GNL3
G protein nucleolar 3.
      
 0.611
POLR3D
RNA polymerase III subunit D.
      
 0.611
MGAT4A
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A.
      
 0.611
LIMD2
LIM domain containing 2.
      
 0.610
PPIF
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
      
 0.558
CACHD1
Cache domain containing 1.
      
 0.548
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.