Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SH3TC2SH3 domain and tetratricopeptide repeats 2. (1250 aa)    
Predicted Functional Partners:
GJB1
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.601
ABLIM2
Actin binding LIM protein family member 2.
      
 0.570
GDAP1
Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily.
      
 0.552
FIG4
FIG4 phosphoinositide 5-phosphatase.
      
 0.548
APOBEC1
Apolipoprotein B mRNA editing enzyme catalytic subunit 1.
  
     0.507
FGD4
FYVE, RhoGEF and PH domain containing 4.
      
 0.485
LRRC74A
Leucine rich repeat containing 74A.
      
 0.483
GLT8D1
Glycosyltransferase 8 domain containing 1.
      
 0.476
GLT8D2
Glycosyltransferase 8 domain containing 2.
      
 0.476
LITAF
Lipopolysaccharide induced TNF factor.
   
  
 0.471
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (30%) [HD]