Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PMEPA1Prostate transmembrane protein, androgen induced 1. (202 aa)    
Predicted Functional Partners:
RPS2
Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.
   
 0.850
ENSAPLP00000028245
Uncharacterized protein.
    
 0.842
SMAD2
Mothers against decapentaplegic homolog.
    
 0.838
SMAD3
Mothers against decapentaplegic homolog.
    
 0.838
SMURF1
E3 ubiquitin-protein ligase.
    
 
 0.717
SETD1B
SET domain containing 1B, histone lysine methyltransferase.
    
 0.684
GAR1
H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
   
 
 0.683
ENSAPLP00000023040
Uncharacterized protein.
   
 0.656
NEDD4
E3 ubiquitin-protein ligase.
    
 
 0.636
NEDD4L
NEDD4 like E3 ubiquitin protein ligase.
    
 
 0.636
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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