Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (630 aa)    
Predicted Functional Partners:
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1.
    
 0.999
MAP3K7
Mitogen-activated protein kinase kinase kinase 7.
   
 0.999
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.999
TAB2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
  
0.997
RIPK1
Receptor interacting serine/threonine kinase 1.
    
 0.989
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.978
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.977
TRADD
TNFRSF1A associated via death domain.
     
 0.970
U3IBK2_ANAPP
Uncharacterized protein.
    
 0.965
RIPK2
Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.
    
 0.965
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (22%) [HD]