Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NLKMitogen-activated protein kinase. (435 aa)    
Predicted Functional Partners:
MAP3K7
Mitogen-activated protein kinase kinase kinase 7.
    
0.995
LEF1
Uncharacterized protein.
    
 0.994
TCF7L1
Uncharacterized protein.
    
 0.984
TCF7L2
Transcription factor 7 like 2.
    
 0.984
ENSAPLP00000032903
HMG box domain-containing protein.
    
 0.951
FOXO1
Forkhead box O1.
    
 0.918
FOXO3
Fork-head domain-containing protein.
    
 0.918
FOXO4
Forkhead box O4.
    
 0.915
FOXO6
Forkhead box O6.
    
 0.915
CTNNB1
Catenin beta 1.
    
 0.885
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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