STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHFRCheckpoint with forkhead and ring finger domains. (677 aa)    
Predicted Functional Partners:
APLF
Aprataxin and PNKP like factor.
      
 0.871
PARP1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
    
 
 0.840
ENSAPLP00000031478
PARP-type domain-containing protein.
    
 
 0.840
PLK1
Serine/threonine-protein kinase PLK.
    
 
 0.830
ERLEC1
Endoplasmic reticulum lectin 1.
   
 0.755
ENSAPLP00000023561
Uncharacterized protein.
     
 0.672
USP7
Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.
    
 
 0.606
PLK2
Serine/threonine-protein kinase PLK.
    
 
 0.601
APTX
Aprataxin.
      
 0.589
PARP3
Poly [ADP-ribose] polymerase.
    
 
 0.575
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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