Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GUCY2CGuanylate cyclase. (1069 aa)    
Predicted Functional Partners:
ENSAPLP00000026725
Uncharacterized protein.
   
 0.999
ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase 3.
     
 0.927
ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase 1.
     
 0.927
NUDT2
Nudix hydrolase 2.
     
  0.900
GCH1
GTP cyclohydrolase 1.
     
 0.855
PDE6C
Phosphodiesterase.
    
 0.854
PDE6B
Phosphodiesterase.
    
 0.853
MOCS1
Molybdenum cofactor synthesis 1.
   
 
 0.853
PDE10A
Phosphodiesterase.
    
 0.850
PDE5A
Phosphodiesterase.
    
 0.833
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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