Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
URB2URB2 ribosome biogenesis homolog. (948 aa)    
Predicted Functional Partners:
URB1
URB1 ribosome biogenesis homolog.
   
  
 0.842
NOL8
Nucleolar protein 8.
   
 
 0.841
WDR1
WD repeat domain 1.
   
 
 0.748
CAPZB
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.723
CAP2
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.660
CAP1
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.660
PFN4
Profilin; Belongs to the profilin family.
   
 0.543
PFN2
Profilin; Belongs to the profilin family.
   
 0.543
ACTR2
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 
 0.505
UBE2F
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 
 0.485
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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